This dialog will open if you click on the Cancel button on the Submit Microarray Hybridization Request window after having entered some data on that window (but not having actually submitted your request to the HCI Microarray Core facility). GNomEx is simply verifying to make sure that you really want to cancel your request, since it has not been submitted yet. Click Yes on this dialog to verify that you really want to close the Submit Microarray Hybridization Request window without submitting a request or No to return to the window and continue with your submission.